Resumen. DELGADO FERNANDEZ, María del Rosario; ROMERO RIVERO, Oscar Luis y DIAZ BORROTO, Abel. Central insipid diabetes: presentation of a case. Articulo en XML; Referencias del artículo; Como citar este artículo; SciELO Analytics; Enviar Neurohypophisis and Insipid Diabetes: A description of a case. Palabras clave: Neurohipófisis [Histología]; Diabetes Insípida [ Diagnóstico];. Existen dos tipos: diabetes insípida (DI) central, debida a la síntesis o liberación defectuosas de arginina vasopresina (AVP) desde el Artículos de referencia.

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Pituitary adenomas with parasellar invasion. Choose one of the access methods below or take a look at our subscribe or free trial options. Artiiculos receptors differ both in their location as well as their functions Table 1.

Dichos defectos facilitan la invasividad del tumor hacia el interior del seno cavernoso. The anti-diuretic hormone arginine-vasopressin AVP is released from the pituitary and xiabetes water reabsorption in the principal cells of the kidney collecting duct.

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The procedure for the test is described below. One of the hormones elaborated in the hypothalamus and carried through the hypothalamic Neurohypophisiary brush until its store place in the neuro hypophysis is the vasopresine. Nephrogenic diabetes insipidus is caused by partial or complete renal resistance to the effects of AVP. A subscription is required to access all the content in Best Practice.

Mean follow up was 15 months.

Therefore, it is necessary to administer a potassium supplement. Can J Neurol Sci ; Introduction Diabetes insipidus is a disease characterized by the elimination of high volumes of very dilute urine.


Adv Neurol ; The alteration induced by these substances is caused by inhibition of the adenylcyclase and cAMP activity in the collecting tubule, and is usually reversible when the medication is stopped. Se continuar a navegar, consideramos que aceita o seu uso. J Clin Endocrinol Metab ; Acta Neurochir Suppl Wien ; Urodynamic studies show a complacent bladder with slow and incomplete emptying, which exacerbates deterioration of renal function ce which procedures such as cystostomy have been required to ensure bladder emptying.

BMJ Best Practice

Based on more in-depth mechanistic understanding, insi;ida therapeutic strategies are current being explored. The disorder usually presents with anterior pituitary failure with preservation of posterior pituitary functions.

J Pediatr Endocrinol Metab.

She needed oral desmopressin on a continuous basis to control polyuria. Studies for the treatment of congenital nephrogenic diabetes insipidus have been recently done through drug stimulation, promoting the transport of the AVPR2 retained in the cytoplasm of the tubulorenal cell to the plasma membrane where it could develop its function. In our experience, despite tumor extension to the cavernous sinus, pituitary macroadenomas can be safely resected with low morbidity and mortality.

Si continua navegando, consideramos que acepta su uso. This disorder is caused by the failure of the posterior pituitary to secrete adequate amounts of arginine vasopressin AVPalso called antidiuretic hormone neurogenic or central diabetes insipidusor by the inability of the kidney to respond to circulating AVP nephrogenic diabetes insipidus. The defect of urine concentration is present from birth so that the clinical manifestations could be observed from the first weeks of life.

En la actualidad, como podemos ver en la tabla 2, ninguno de los pacientes con resecciones totales o subtotales ha necesitado RDTEF. Among the different groups of patients with nephrogenic diabetes insipidus due to a secondary interstitial tubular disease, one of the most important is that caused by kaliopenic nephropathy which presents in children with severe malnutrition.


Zelikovic I, Eisenstein I, editors. There is a reduction of the sodium concentration and total solutes in the interstitium of the renal medulla in qrticulos patients. Sign up for a FREE trial.


Other studies are directed at achieving the direct stimulation of the retained AVPR2 or directly stimulate the function of aquaporin-2 without the need of the participation of AVPR2. Transsphenoidal neurosurgery of intracranial neoplasm. The Herbert Olivecrona lecture. Anatomic changes in the renal medulla are frequently seen in patients with primary tubulointerstitial nephropathies, which modify the osmolar gradient dependent on the action of the mechanisms of the multiplication of the countercur-rent and cause the development of polyuria.

Nat Rev Drug Discov. Cavernous sinus invasion by pituitary adenomas. In addition, she developed Polyuria.

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Endoscopic endonasal approaches to the cavernous sinus: Congenital nephrogenic diabetes insipidus is a disorder associated with mutations in either the AVPR2 or AQP2 gene, causing the inability of patients to concentrate their urine.

Under these conditions, se is advisable to perform a test of urinary concentration, which consists of stimulating the maximum renal concentration in response to water restriction.

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